Hello everyone. I am relatively new to the NEURON software. However, I do know some of the basics. I use the newest version of neuron on windows. The project I am working on requires me to measure the different levels of EPSP that are being created by different neurons. Let me try to illustrate this.
A, B, C > D
D > E
D < E
So.. basically, Neuron A, B, C input information to Neuron D. Then neuron D inputs information onward to neuron E which then send its signal back to neuron D. All these connections produce an EPSP. The gist of the project is to show the different levels of EPSP response produced by different pairs of cells.
So, my question is very simple. What method do you recommend I take to make the model. I have tried to used network builder and have come very far but the problem is that I do not know how to record the EPSP. All I get are AP's.
Is there any way in network builder I can get EPSP's.
OR is the only solution to the problem the creation of a new pointer?
Thank you for your time!
PS. At the moment, all I want to do is get a model made. Specific properties like the specifics of the Hodgkin-Huxley model or the passive model are not important, at least for now.
Help with modeling EPSP in the auditory system
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Clearly you're getting EPSPs or you wouldn't be getting spikes--at least not synaptically-
triggered spikes. If you want to see only EPSPs and no spikes in the target cell, just reduce
synaptic weight (weight of the NetCon that drives the activated synapse).
Of course, if you reduce synaptic weights to the point where the EPSPs aren't big enough
to trigger spikes, your network won't do much, but at least you'll be able to see temporal
summation of different inputs.
None of this has anything to do with whether you construct your network with the GUI or
by writing hoc code.
triggered spikes. If you want to see only EPSPs and no spikes in the target cell, just reduce
synaptic weight (weight of the NetCon that drives the activated synapse).
Of course, if you reduce synaptic weights to the point where the EPSPs aren't big enough
to trigger spikes, your network won't do much, but at least you'll be able to see temporal
summation of different inputs.
None of this has anything to do with whether you construct your network with the GUI or
by writing hoc code.