plasticity, converging synapses, integrate and fire model

[Cal]

Okay, some background context:
A while back I (sort of) figured out how to use NetCon:
http://www.neuron.yale.edu/phpBB/viewto ... =15&t=1778

Then I learned how to add use-dependent plasticity with my synapses:
http://www.neuron.yale.edu/phpBB/viewto ... =16&t=1972

= Which I put together to connect to a single compartment neuron.

great, but now I've been asked to simplify and connect all of these to a simple integrate and fire neuron.

Looking at ModelDB I found a potential starting point with a COBA http://senselab.med.yale.edu/modeldb/Sh ... 3319&file=\

So far I've done this:

Code: Select all

create soma

soma {
  nseg = 1
  diam = 76.58	
  L = 100
  cm = 1
}

forall {
	insert pas
	g_pas = 5e-05
	e_pas = -60
}

Dt = 0.02
npoints = 40000
trans = 0

dt = 0.02
tstart = trans
tstop = trans + npoints * Dt
runStopAt = tstop
steps_per_ms = 1/Dt
tstep = dt

objref spkout
soma spkout = new SpikeOut(.5)

thresh_SpikeOut = -50	// (mV)
refrac_SpikeOut = 5	// (ms)
vrefrac_SpikeOut = -60	// (mV) reset potential
grefrac_SpikeOut = 100	// (uS) clamped at reset

InputSpikes()

objref dv
dv = new Vector()
dv.record(&soma.v(.5))

run()
tracesave2()

InputSpikes() and tracesave2() handle the NetCon/synaptic inputs and saving voltage traces, respectively.

Ok, so first question: Looking at SpikeOut.mod, theres a NETRECEIVE command. So I know I have to connect it ... somewhere. Where do I go from here?

[ted]

I'd think one of these would be more appropriate:
Synaptic plasticity: pyramid->pyr and pyr->interneuron (Tsodyks et al 1998), accession # 3815 in ModelDB.
Short term plasticity of synapses onto V1 layer 2/3 pyramidal neuron (Varela et al 1997) accession # 3264 in ModelDB.