I have a point-process NMDA receptor mechanism (NMDASyn) that I'd like to place at the center of my single-compartment neuron. However, rather than have just one instance of NMDASyn, I'd like a new one for every connection my cell makes. Is it OK to have all these instances of NMDASyn placed at the same location in my cell? How should I expect their effects on V_m to be summed?
Thanks,
Dan
Receptor Mechanisms at the Same Location on a Cell
-
- Site Admin
- Posts: 6300
- Joined: Wed May 18, 2005 4:50 pm
- Location: Yale University School of Medicine
- Contact:
Re: Receptor Mechanisms at the Same Location on a Cell
Yes.dabliss wrote:Is it OK to have all these instances of NMDASyn placed at the same location in my cell?
Each one will generate its own current. NEURON knows how to deal with charge balance.How should I expect their effects on V_m to be summed?