Search found 37 matches

by ahmed.hamzah
Wed Jun 27, 2018 12:33 pm
Forum: Other questions
Topic: Sodium and Potassium current
Replies: 6
Views: 1745

Re: Sodium and Potassium current

Than again. no one near me can help me, but can i post my code and then maybe you can guide me to get the solution?
by ahmed.hamzah
Tue Jun 26, 2018 6:52 pm
Forum: Other questions
Topic: Sodium and Potassium current
Replies: 6
Views: 1745

Re: Sodium and Potassium current

Thank you for replay. The problem is that after injecting current inside soma, it should all concentrations (Na,Kand ca) get back to them resting value, but I got the sodium concentration lower than the resting value (initial 10 mM while Igot 5mM),and for potassium concentration i got higher than th...
by ahmed.hamzah
Sun Jun 24, 2018 1:34 pm
Forum: Parallel NEURON
Topic: Stabilization Mechanism
Replies: 9
Views: 2220

Re: Stabilization Mechanism

Thank you for the information, actaully I am looking for someone who work in both Na and K concentrations in MdeloelDB for a couple days but I could not find one. Can you help me to in this issue.
by ahmed.hamzah
Fri Jun 22, 2018 6:18 pm
Forum: Other questions
Topic: Sodium and Potassium current
Replies: 6
Views: 1745

Sodium and Potassium current

I am working on model of soam using three different voltage gated channels Na,K and Ca, three different leak channels and three different channels of pump for the same ion. I am trying to use theses channels to get a resting value of concentrations after injecting it with certain current u=in the mi...
by ahmed.hamzah
Thu Jun 21, 2018 1:38 pm
Forum: Parallel NEURON
Topic: Stabilization Mechanism
Replies: 9
Views: 2220

Re: Stabilization Mechanism

After adding this condition to the na/K pump BREAKPOINT { inapump = ipumpmax*(1/(1 + pow(km/nai,n))) if(nai <= 10 ){ inapump = 0 }else{ inapump = ipumpmax*(1/(1 + pow(km/nai,n))) } ina = 3.0*inapump if(ki >= 140 ){ inapump = 0 }else{ inapump = ipumpmax*(1/(1 + pow(km/nai,n))) } ik = -2.0*inapump } T...
by ahmed.hamzah
Thu Jun 21, 2018 12:49 pm
Forum: Parallel NEURON
Topic: Stabilization Mechanism
Replies: 9
Views: 2220

Re: Stabilization Mechanism

Thanks for those information. I used that Nadifl.mod in my file.hoc. regarding to the Nadifl.mod, does that file included calculate diffusion and migration terms, that is , {diffusion constant *delta(concentration)/dlta(x)}+{mobility * concentration* delta(poteial )/delta (x)} or just {diffusion con...
by ahmed.hamzah
Tue Jun 19, 2018 5:27 pm
Forum: Parallel NEURON
Topic: Stabilization Mechanism
Replies: 9
Views: 2220

Re: Stabilization Mechanism

Once again thank you. The concentrations has been calculated at nadifl, kdifl and cadifl .mod , so do I have to add the concentrations calculation in the same pump file or I can do it separately like what I did. Secondly, after doing your correction to the code I still have problem with potassium co...
by ahmed.hamzah
Tue Jun 19, 2018 2:20 pm
Forum: Parallel NEURON
Topic: Stabilization Mechanism
Replies: 9
Views: 2220

Re: Stabilization Mechanism

Thank you for replay, the flowing are the file.hoc nad pump.mod Which I used in my code. [create soma soma { nseg = 101 L = 100// [µm] length diam = 0.1 // [µm] diameter insert hh gnabar_hh = 0.120 // [S/cm^2] gkbar_hh = 0.036 // [S/cm^2] glbar_hh = 0.0000 // [S/cm^2] //gcabar_hh = 0.12 // [S/cm^2] ...
by ahmed.hamzah
Mon Jun 18, 2018 1:43 pm
Forum: Parallel NEURON
Topic: Stabilization Mechanism
Replies: 9
Views: 2220

Stabilization Mechanism

I am trying to simulate soma with sealed ends. I have used three ions Na, K and Ca, and injected current was 50 pA for 0.2 ms duration the length of this soma 100 micro-meter and diam=0.1 micrometer. I used three voltage gated channels for Na,K and Ca and Na/K pump. I am trying to find the concentra...
by ahmed.hamzah
Wed Jun 13, 2018 3:20 pm
Forum: NEURON + Python
Topic: Neuron code
Replies: 20
Views: 6133

Re: Neuron code

[Second step: Use your browser to search the hits for the exact string
WRITE nai
or
WRITE ki
Case is important! Avoid any hits that
WRITE Nai
or
WRITE Ki]
can you tell me how ?
by ahmed.hamzah
Wed Jun 13, 2018 12:02 pm
Forum: NEURON + Python
Topic: Neuron code
Replies: 20
Views: 6133

Re: Neuron code

I would like to use activation mechanism of calcium is similar to that of sodium current channel, so is there a simple way to do that by using the standard HH for sodium to my max. calcium conductance?
by ahmed.hamzah
Tue Jun 12, 2018 4:43 pm
Forum: NEURON + Python
Topic: Neuron code
Replies: 20
Views: 6133

Re: Neuron code

Does the low threshed calcium current model different from squid to the others.
by ahmed.hamzah
Mon Jun 11, 2018 1:39 pm
Forum: NEURON + Python
Topic: Neuron code
Replies: 20
Views: 6133

Re: Neuron code

Thank you.The last comment was important.
by ahmed.hamzah
Mon Jun 11, 2018 1:08 pm
Forum: NEURON + Python
Topic: Neuron code
Replies: 20
Views: 6133

Re: Neuron code

So in this case I have to create file.mod to calculate calcium current . Is there example I can use it for this purpose ?
by ahmed.hamzah
Mon Jun 11, 2018 12:25 pm
Forum: NEURON + Python
Topic: Neuron code
Replies: 20
Views: 6133

Re: Neuron code

Thank you Ted. I am trying to add calcium to my code but when drew the calcium concentration with time there is no curve show up in the graph. insert hh gnabar_hh = 0.120 // [S/cm^2] gkbar_hh = 0.036 // [S/cm^2] glbar_hh = 0.0003 // [S/cm^2] gcabar_hh = 0.32 // [S/cm^2] cm=1 // [uF/cm2] Ra=89.9 //oh...