Search found 5 matches
- Sun Nov 03, 2013 7:40 pm
- Forum: General questions and discussions about computational neuroscience
- Topic: measured vs specific Rm
- Replies: 7
- Views: 33487
Re: measured vs specific Rm
Hi Ted, I am performing patch-clamp experiments and the estimate of tau comes from a depolarisation step. This is a standard protocol called seal test or sometimes membrane test. Thanks for raising a number of interesting points. I am trying to look into action potential backpropagation, hence I was...
- Sun Nov 03, 2013 3:09 pm
- Forum: General questions and discussions about computational neuroscience
- Topic: measured vs specific Rm
- Replies: 7
- Views: 33487
Re: measured vs specific Rm
Hi Ted, Thanks again for taking time to respond to my questions. The half width of a spike is only about 1 ms, much shorter than membrane time constant Actually, the time constants that I am seeing are on the same order as my AP half widths, around 1.5 ms (measured at the soma, granted). Where exact...
- Sun Nov 03, 2013 10:21 am
- Forum: General questions and discussions about computational neuroscience
- Topic: measured vs specific Rm
- Replies: 7
- Views: 33487
Re: measured vs specific Rm
Hi Ted, Thanks very much for getting back to me and sorry for not clarifying enough. In myelinated or nonmyelinated axon? Prediction for nonmyelinated axon: Rm has no effect as long as membrane isn't grossly leaky. In nonmyelinated axons. Why do you say that it won't have any effect? Surely tau is g...
- Fri Nov 01, 2013 9:28 pm
- Forum: General questions and discussions about computational neuroscience
- Topic: measured vs specific Rm
- Replies: 7
- Views: 33487
measured vs specific Rm
Hi all, I would like to see how conduction velocity changes in response to changes in membrane resistance. Not just theoretically though, but using experimentally determined values. From whole-cell voltage clamp experiments I have estimates of the conduction velocity, membrane resistance and membran...
- Mon Feb 06, 2006 12:24 pm
- Forum: Getting started
- Topic: IPSP/EPSP
- Replies: 1
- Views: 4233
IPSP/EPSP
Hi there, I am a complete newbie to NEURON and just want to replicate some data from a paper. So, I installed NEURON and downloaded the model they are using (Stuart and Spruston, 1998). Everything works fine so far. Now they talk about simulating an IPSP by a conductance change with reversal potenti...