## Search found 10 matches

Fri Jul 19, 2024 4:44 am
Forum: NEURON + Python
Topic: Diameter of a Squid Giant Axon Model
Replies: 6
Views: 9551

### Re: Diameter of a Squid Giant Axon Model

Oh, I just saw the reply, I wasn't expecting any, so didn't come and check then. 2. Assume that the cell's response can be regarded as the superposition of two components that start at the beginning of the current pulse: a damped sinusoid of the form Asin*sin(w*T)*exp(T/tausin) where w = 2*PI*f, and...
Fri Jul 19, 2024 3:17 am
Forum: Getting started
Topic: Questions about "stylized" model and build a new n
Replies: 5
Views: 3355

### Re: Questions about "stylized" model and build a new n

Thank you so much, for the detailed response on my query. I wanted to report a (approximate) technique to model ultrasound neuromodulation on NEURON models. As you recommended, I wanted to show it on a simplified model. I felt this "stylized" model is a good candidate, but I was wondering ...
Wed Jul 17, 2024 4:03 am
Forum: Getting started
Topic: Questions about "stylized" model and build a new n
Replies: 5
Views: 3355

### Re: Questions about "stylized" model and build a new n

Hello Ted, Thanks for the directions, I understood the structure and mechanisms of "stylized" HH neuron model. I am curious, though, what were the references for building such a model? How did you decide the values for the membrane mechanisms and morphology? Were they just random values ch...
Mon Jul 01, 2024 2:27 am
Forum: NEURON + Python
Topic: Can't we write tautable.hoc in Python?
Replies: 2
Views: 5834

### Re: Can't we write tautable.hoc in Python?

But I can't find a python statement equivalent to the following HOC statement:

Code: Select all

`` table_tabmtau_KIR(&vecmtau_KIR.x[0], vecv_KIR.size, &vecv_KIR.x[0]) ``
Fri May 24, 2024 3:36 am
Forum: NEURON + Python
Topic: Can't we write tautable.hoc in Python?
Replies: 2
Views: 5834

### Can't we write tautable.hoc in Python?

I wonder if we still need to write tautables in hoc, then include in the python script? For example, for the following hoc script: // Tautable for KIR channel objref vecv_KIR, vecmtau_KIR vecv_KIR = new Vector() vecv_KIR.indgen(-100, 0, 10) // -100 to 0 with steps of 10 vecmtau_KIR = new Vector() ve...
Fri Mar 01, 2024 1:22 am
Forum: NEURON + Python
Topic: Diameter of a Squid Giant Axon Model
Replies: 6
Views: 9551

### Re: Diameter of a Squid Giant Axon Model

Woww! This is going into deep waters. But yeah, I got the idea of why the oscillations happen. Thank you once again for your quick and informative reply as always. So, the perceived inductance is not real, the oscillation is caused by the involvement of active channels, huh! I tried the experimental...
Thu Feb 29, 2024 12:04 am
Forum: NEURON + Python
Topic: Diameter of a Squid Giant Axon Model
Replies: 6
Views: 9551

### Re: Diameter of a Squid Giant Axon Model

Thanks, this makes sense now. I have one more question regarding squid axon behavior (not sure if I should post it as a separate post in the forum). When I use the default HH axon (L=100, diam = 500, celsius = 6.3) and stimulate it with a step current (IClamp, amp = 1, delay = 1000, dur = 300), I ge...
Tue Feb 27, 2024 4:13 am
Forum: NEURON + Python
Topic: Diameter of a Squid Giant Axon Model
Replies: 6
Views: 9551

### Diameter of a Squid Giant Axon Model

Hello everyone, when you create a new section in NEURON, the default length of the section will be 100 um, the diameter will be 500 um, and the temperature will be 6.3 degrees Celsius. I guess this is in accordance with the properties of squid giant axon. But then why do the dimensions in the "...
Fri Apr 28, 2023 6:04 am
Forum: NEURON + Python
Topic: What is a NEURON equivalent of a point-neuron?
Replies: 3
Views: 20995

### Re: What is a NEURON equivalent of a point-neuron?

Thanks a lot for your clarification. I wasn't very thorough with the experiment. There was a mistake in evaluating the area as well. I included the flat surfaces of the soma for the computation. It seems only the curved surface area of the cylinder is involved in the ion conductance - is that so? Ea...
Thu Apr 13, 2023 12:24 pm
Forum: NEURON + Python
Topic: What is a NEURON equivalent of a point-neuron?
Replies: 3
Views: 20995

### What is a NEURON equivalent of a point-neuron?

It is possible to define a dimensionless point neuron without using NEURON simulation environment as below: import numpy as np from scipy.integrate import solve_ivp # Define the Hodgkin-Huxley model parameters Cm = 1.0 # membrane capacitance (uF/cm^2) gNa = 120.0 # maximum sodium conductance (mS/cm^...