Search found 12 matches
- Fri Nov 23, 2018 4:26 pm
- Forum: General questions and discussions about computational neuroscience
- Topic: tES and suprathreshold E
- Replies: 2
- Views: 1629
Re: tES and suprathreshold E
Thanks, Ted!
- Tue Nov 20, 2018 10:23 pm
- Forum: General questions and discussions about computational neuroscience
- Topic: tES and suprathreshold E
- Replies: 2
- Views: 1629
tES and suprathreshold E
In transcranial electric stimulation (TES) the applied E field amplitude at the level of the targeted cortex underneath the electrode is approximately 0.5V/m. Typically not more than 2mA of current is applied at the scalp electrodes to achieve such an E field amplitude. It’s not possible to go much ...
- Sat Nov 10, 2018 8:02 pm
- Forum: General questions and discussions about computational neuroscience
- Topic: Transfer impedance tool
- Replies: 1
- Views: 1487
Transfer impedance tool
I have been using the impedance tool in neuron and would like to understand it’s origin in more depth than appears in the documentation. In particular I would like a better understanding of how the transfer impedance (as calculated by NEURON) follows from the active cable equation and under what ass...
- Tue Nov 06, 2018 3:45 pm
- Forum: General questions and discussions about computational neuroscience
- Topic: Passive membrane impedance vs voltage-gated conductance
- Replies: 5
- Views: 2275
Re: Passive membrane impedance vs voltage-gated conductance
Thanks Ted!
What about for pyramidal cells? Can my question be answered definitively for them?
Cheers!
What about for pyramidal cells? Can my question be answered definitively for them?
Cheers!
- Tue Nov 06, 2018 3:43 pm
- Forum: General questions and discussions about computational neuroscience
- Topic: Subthreshold spontaneous oscillations
- Replies: 5
- Views: 2224
Re: Subthreshold spontaneous oscillations
Hi Ted I (a physicist) am a newbie to the detailed understanding of electrophysiology so I really appreciate your feedback! I guess this is what I am trying to get my head around: I am assuming that there presently exists a model for spontaneous oscillations in neurons (spontaneous in a manner simil...
- Mon Nov 05, 2018 10:36 pm
- Forum: General questions and discussions about computational neuroscience
- Topic: Passive membrane impedance vs voltage-gated conductance
- Replies: 5
- Views: 2275
Re: Passive membrane impedance vs voltage-gated conductance
Hi Ted
I am not sure that answers my question.
I am not sure that answers my question.
- Mon Nov 05, 2018 10:33 pm
- Forum: General questions and discussions about computational neuroscience
- Topic: Subthreshold spontaneous oscillations
- Replies: 5
- Views: 2224
Re: Subthreshold spontaneous oscillations
Hi Ted
By intrinsic subthreshold oscillations I mean spontaneous subthreshold oscillations. Presumably the model must account for spontaneous oscillations much differently than oscillations that are forced upon it by an extrinsic source.
By intrinsic subthreshold oscillations I mean spontaneous subthreshold oscillations. Presumably the model must account for spontaneous oscillations much differently than oscillations that are forced upon it by an extrinsic source.
- Sun Nov 04, 2018 11:20 pm
- Forum: General questions and discussions about computational neuroscience
- Topic: Passive membrane impedance vs voltage-gated conductance
- Replies: 5
- Views: 2275
Passive membrane impedance vs voltage-gated conductance
At subthreshold levels of injected current I am guessing that the passive membrane conductance is much greater than the conductance of voltage-gated channels. Is this true? If so then at what transmembrane potential do the voltage-gated conductances start to dominate. Bit of a newbie question!
- Sun Nov 04, 2018 5:18 pm
- Forum: General questions and discussions about computational neuroscience
- Topic: Subthreshold spontaneous oscillations
- Replies: 5
- Views: 2224
Subthreshold spontaneous oscillations
Some neurons display intrinsic spontaneous subthreshold oscillations. For subthreshold extrinsic (applied) electrical stimuli (current injection or magnetic induction) the HH equations can often be linearized and the solutions of these equations are good predictors in this subthreshold regime. My qu...
- Thu Oct 25, 2018 1:23 am
- Forum: Getting started
- Topic: Frequency response function
- Replies: 4
- Views: 1665
Re: Frequency response function
Thanks Ted
I will be taking a look very soon. This is great!
Yep, I figured you had spikes on your mind hence my gentle nudge back toward the subthreshold and linear systems.
I will be taking a look very soon. This is great!
Yep, I figured you had spikes on your mind hence my gentle nudge back toward the subthreshold and linear systems.
- Wed Oct 24, 2018 10:38 pm
- Forum: Getting started
- Topic: Frequency response function
- Replies: 4
- Views: 1665
Re: Frequency response function
Ted
Subthreshold systems are often described by linearized equations. At steady state they will oscillating at the driving frequency of the input current. No spikes are produced. The Fourier transform of the response is called the frequency response of the system.
Subthreshold systems are often described by linearized equations. At steady state they will oscillating at the driving frequency of the input current. No spikes are produced. The Fourier transform of the response is called the frequency response of the system.
- Wed Oct 24, 2018 8:18 pm
- Forum: Getting started
- Topic: Frequency response function
- Replies: 4
- Views: 1665
Frequency response function
Hi
I am new to NEURON. Does it have a means for calculating the frequency response function between input (injected curren) and output (membrane potential) sites for subthreshold stimuli using a linear model?
Thank you!
I am new to NEURON. Does it have a means for calculating the frequency response function between input (injected curren) and output (membrane potential) sites for subthreshold stimuli using a linear model?
Thank you!