Search found 3 matches

by jofrony
Wed Nov 18, 2020 1:25 pm
Forum: NEURON + Python
Topic: Modelling of subcellular signalling
Replies: 1
Views: 363

Modelling of subcellular signalling

Hi, I am using NEURON to simulate g-protein coupled receptor signalling. I was wondering if there is a specified way in neuron to send information between point process object and distributed membrane mechanisms (for example ion channels). I have three mechanisms which I would need to have communica...
by jofrony
Mon Nov 25, 2019 5:05 am
Forum: Adding new mechanisms and functions to NEURON
Topic: Failure rates in synapse model
Replies: 0
Views: 1077

Failure rates in synapse model

Hi, We are currently using a tmGlut model . We would like to have a failure rate in the net_recieve block to capture the certain dynamics of our connections. Is there a method in the NMODL which allows for handling some randomisation...
by jofrony
Tue Nov 12, 2019 6:20 am
Forum: NEURON + Python
Topic: Frequency dependent activation of g protein models
Replies: 2
Views: 3750

Frequency dependent activation of g protein models

Hi, I am working on NEURON+python implementation of neuromodulatory synapses. I have models for M4 receptors which takes a acetylcholine concentration as input parameter and a nitric oxide model which is a slow excitatory current ( using the Exp2syn but with modified time constants). I was wondering...