Search found 3 matches

by gsb
Thu Aug 17, 2017 3:11 pm
Forum: Optimization
Topic: using MRF for fitting two outputs at same time
Replies: 6
Views: 17449

Re: using MRF for fitting two outputs at same time

Thanks, Ted. That is certainly a convenient method for cases with simple point processes like IClamp/SEClamp. Let's say I also had a segment that implemented pipette capacitance, in between the cell and the IClamp. Would it be reasonable to set the internal resisitivity of this segment to 1e9 -- or ...
by gsb
Thu Aug 17, 2017 2:34 pm
Forum: Optimization
Topic: using MRF for fitting two outputs at same time
Replies: 6
Views: 17449

Re: using MRF for fitting two outputs at same time

Thank you for the reference, Ted. I hadn't realized that their fitting setup would also be available on ModelDB. (In case anyone else might be looking for examples of MRF setup, its in the model's cell2 folder. Despite the readme file, it took me a moment to realize.) It was definitely worth the loo...
by gsb
Wed Aug 16, 2017 1:36 pm
Forum: Optimization
Topic: using MRF for fitting two outputs at same time
Replies: 6
Views: 17449

Re: Best practices for MRF fit on multiple configurations

I'm also using the MRF to fit simulation data from multiple generators. In one case, the instrumentation changes, and I'd like to fit the (hopefully constant) passive properties of the cell that was recorded. I'm also using a reconstruction of the cell's morphology (hopefully also constant and held ...