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Hi. I have a couple of questions about Coreneuron before starting to change my current simulation environment. 1) Based on posts on NEURON github, Coreneuron can be run on CPUs and I was wondering if it supports multisplit? 2) If yes, coreneuron + multisplit can provide a boost to the simulation tim...

Hi. For nrnivmodl was ok but for modlunit is not and the voltage clamp showed that too. alpha = 50exp(e * 1.2 * v/(boltzmann *(273.15 + celsius))) The previous expression needs the conversion factor (1000) My issue is where i have to apply the conversion factor. If I simply multiply everything for 1...

Thank you.

I have added the two costant as UNITS and the MOD files pass nrnivmodl without issues.

My bad, I forgot to write that the equation will be used in a MOD file.

Hi. I would need some help to translate an equation, I found on a paper, into the correct NEURON equivalent. This equation controls the forward transition between two states in a markov chain. alpha = ao exp(eo zada E/kT) ao is an integer calculate by the authors, eo is the elementary charge, zada i...

HI.

Thank you for the explanation.

Hi. I was looking to this old thread (https://www.neuron.yale.edu/phpBB/viewtopic.php?p=14858&hilit=avx#p14858) about compiling NEURON with AVX. Now that AVX-256 and AVX-512 are common on desktop CPU, I was wondering if it was possible to add a flag, during the configure, to compile NEURON for o...

Never mind.

I have just resolved my issues directly with the seclamp MOD file.

Hi. I need to write a protocol containing: a voltage clamp for x second, followed by a current clamp for y seconds and again a voltage clamp for x second. The functions Vclamp and Seclamp do no have a delay option and, as for the documentation, "Do not insert several instances of this model at ...

Hello Ted.

Thank you very much.
I was missing the "mass balance equation".
I have added it to the MOD file and everything is working fine.

Best
Stefano

Hi. My workflow contains the following steps: a substance is generated into a section (MOD file), is pumped out (MOD file) in a cubic ECS (RxD). Than from the ECS it is pumped (MOD file) into another section where there are a series of reactions (RxD). This works fine. Now I'm trying to substitute t...

Never mind. I have found the underlying issue.

Hi. I'm trying to define a MOD file capable of reading the internal concentration of a substance and, with a slim to none delay, "transpose" the same concentration in a ecs. The ecs is defined with rxd.Extracellular(). The substance is generated by a MOD file in the inside and as an rxd.sp...

Thank you. I have modified your code and i can reproduce the strangeness. from neuron import h, rxd from neuron.units import mV, ms h.load_file('stdrun.hoc') soma = h.Section(name='soma') dend0 = h.Section(name='dend0') dend00 = h.Section(name='dend00') dend00.insert('pump') dend1 = h.Section(name='...

Hi. I was checking my RxD code, after implementing it into a multi compartmental model and something very odd came up. I have a substance, produced by a few dendrites and, trough pumps (the same used in the RxD examples) diffused into the ECS. If I cancel the code responsible for the generation of t...