www.neuron.yale.edu

ted wrote: I wasn't asking what happened to z. The point of my question was to find
out how your model behaves when A is 0.

In this case (A = 0) it behaves like the mechanism (I_m) is NOT calcium dependent: increasing gbar hyperpolarizes the cell, decreasing gbar depolarizes the cell.

Are you saying that increasing this mechanism's gbar hyperpolarized the cell when this mechanism was not Ca dependent, but depolarized it after you made it Ca dependent? Yes I am... If so, what happens when you reduce A to 0? In this case, z=1, as it was when the mecahnism wasn't Ca dependent. But ...

Thanks for your answer. I did as you said and here is the related parts from the mod file: -------------------------------------------------------------------- NEURON { USEION k READ ek WRITE ik USEION ca READ cai } PARAMETER { cai (mM) IC50 = 0.0001004 (mM) A = .868 n = 1.03 frc = 1 ikk } BREAKPOIN...

Hi, I want to describe a voltage dependent channels (e.g KDr, KM) as voltage AND calcium dependent in a way that calcium INHIBITS the channel. The "degree" of inhibition is defined according to the following function: y = A * ((cai*X))/ (((cai*X)) + (Z)) ; A,Z,X are defined elsewhere). wha...

hi all, I'm using the following code: objref vvec, tvec ,vx, i1, i2 vvec = new Vector() tvec = new Vector() tvec.record(&t) soma vvec.record(&v(0.5),tvec) i1 = tvec.indvwhere(">=", t1) //t1, t2 are defined elsewhere i2 = tvec.indvwhere("<=", t2) vx = vvec.c(i1+1, i2) When...

Thanks for the answer. I'll take into consideration the last offer ...

Hi, I'm using NEUON under winXP on a pentium 4 computer, cpu 4 GHz, RAM 2 GB. When I run simulation (of a single neuron) without any other program running in the background I see that the CPU usage is almost 100%. Should I increase the CPU speed in order to get 'faster' results? Thanks in advance, -...

thanks.

--Udi.

still does not work...

Thanks for the quick response.

Regarding the *.ps -
I work under winXP, NEURON version 5.7. I could not find the line in the nrn.def file.

about the idraw, it works.

thanks again.

1. When I try to save a NEURON window as a *.ps file, I get 0 kb file... What can be the problem?

2. How can I edit NEURON figures in other photo editors (eg - CorelDRAW) ?

Thanks in advance.

Hi,
I want to compare the size of different ADPs. How do I calculate the area under the curve (e.g - start point is the end of the fAHP / repolarization, end point is RP)?

Thanks in advance,
--Udi.

I want to simulate the affect of somtic current injection in order to hyperpolarize the cell resting potetial. When I do it in the lab I inject negative DC current to the soma during the experiment. When using NEURON, is it sufficient to change Vm (e.g -80 instead of -65) instead of negative current...