# Hodgkin - Huxley axon

## Physical System

From http://www.mbl.edu

## Model

### Hodgkin-Huxley cable equations

## Simulation

### Representation

    	create axon
    	axon {
    		nseg = 75
    		diam = 100
    		L = 20000
    		insert hh
    	}

### Using the Representation

Run NEURON with above spec.

## Exercises

1) Stimulate with current pulse and see a propagated action potential.

The basic tools you'll need from the NEURON Main Menu :
Tools / Point Processes / Manager / Point Manager to specify stimulation
Graph / Voltage axis and Graph / Shape plot to create graphs of v vs t and v vs x.
Tools / RunControl to run the simulation

2) Change excitability by adjusting sodium channel density.

Tool needed:
Tools / Distributed Mechanisms / Viewers / Shape Name

3) Use two current electrodes to stimulate both ends at the same time.

4) Up to this point, the model has used a very fine spatial grid (nseg = 75).
Change nseg to 15 and see what happens.

Help reference

NEURON hands-on course
Copyright © 1998-2001 by N.T. Carnevale and M.L. Hines, all rights reserved.